A study explores the effects of resveratrol on Alzheimer’s disease
A team of scientists from the Georgetown University Medical Center (USA) has presented an interesting study on the effects of resveratrol , a natural compound present in the Alzheimer’s Association International Conference in Toronto, Canada. red wine, raspberries , blueberries or dark chocolate, about Alzheimer’s disease.
Experts have discovered that this natural phenol appears to restore the integrity of the blood-brain barrier, which decreases the ability of harmful immune molecules to infiltrate from the body into brain tissues.
In their experiment, the researchers examined specific molecules of the cerebrospinal fluid taken from a group of participants with Alzheimer’s . Of all participants 19 of them received a placebo and the remaining 19 became part of a daily treatment with resveratrol, with an amount equivalent to that found in about 1,000 bottles of red wine.
After 12 months, patients who had been treated with the compound had a 50% reduction in the levels of metalloproteinase-9 (MMP-9) in the cerebrospinal fluid.. Considering that high levels of MMP-9 cause a breakdown of the blood-brain barrier, and that proteins and molecules enter it, resveratrol acted as a sustainer of this barrier. Thus, the reduction of neuronal inflammation decreased the cognitive deterioration of the participants , in comparison with the group that was taking the placebo.
” These new findings are very interesting , as they increase our understanding of how resveratrol may be clinically beneficial for people with Alzheimer’s disease. In particular, they point out the importance of the role of inflammation in the disease and the potent anti-inflammatory effects of resveratrol, “says Scott Turner, leader of the study.